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FAMRI Bland Lane Center of Excellence on Secondhand Smoke

About the FAMRI Bland Lane Center of Excellence on Second Hand Smoke at UCSF (formerly called the FAMRI Center of Excellence on Secondhand Smoke)

The FAMRI Bland Lane Center of Excellence on Second Hand Smoke at UCSF is supported by the National Flight Attendant Medical Research Institute (FAMRI) program. FAMRI is funded through a settlement from a class action lawsuit against tobacco companies on behalf of flight attendants who sustained health problems due to exposure to second hand smoke in their job.

The goals of the FAMRI Bland Lane Center of Excellence on Second Hand Smoke at UCSF are to identify relationship between SHS exposure and pulmonary disease progression; develop methods for early detection of SHS-related cardiovascular disease; assess impact of SHS exposure on patients with pulmonary disease develop novel biomarkers of SHS exposure with validation in relation to disease progression; identify factors that influence the development and implementation of smoking restriction policies, and strategies to overcome barriers; and to estimate the economic impact of SHS on cardiovascular disease in the U.S.

The center consists of a research clinic and scientists conducting research in areas of second hand smoke and pulmonary disease, cardiovascular disease, exposure assessment, health, economics and public policy. 

The FAMRI Clinic

The FAMRI Bland Lane Center of Excellence on Second Hand Smoke at UCSF has just launched an online secondhand smoke registry for flight attendants. If you are a flight attendant, over the age of 40 with a minimum of 5 years flight experience,  please CLICK HERE and fill out this questionnaire on your health and (if any) secondhand smoke exposure history, so that we can learn more about the effects of secondhand smoke exposure on your health. For information about the FAMRI Clinic at UCSF, including the nature of the examination and testing and how to make an appointment, click here

Our investigators and the general area of their research are as follows.

 

Pulmonary Research

Mehrdad Arjomandi, MD

John Balmes, MD
Paul Blanc, MD, MSPH
Mark Eisner, MD, MPH

Warren Gold, MD

Suzaynn Schick, PhD

 

Cardiovascular Research

Rita Redberg, MD

 

Exposure Assessment Research

John Balmes, MD

Neal L. Benowitz, MD

S. Katharine Hammond, PhD
Peyton Jacob III, PhD

Suzaynn Schick, PhD

 

Policy Research

Lisa Bero, PhD

Dorie Apollonio, PhD

Wendy Max, PhD

Hai-Yen Sung, PhD

 

Genetics Research

Esteban Burchard, MD

Shweta Choudhry, PhD

 

 


Faculty Member:  Mark Eisner
Impact of SHS Exposure on Adults with COPD and other Airway Diseases

This project examines the impact of secondhand tobacco smoke (SHS) exposure on the risk of developing Chronic Obstructive Pulmonary Disease (COPD). Co-Investigators: John Balmes, MD, Paul D. Blanc MD, MSPH, Katharine Hammond PhD
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Faculty Member:  Neal Benowitz
Secondhand Smoke Exposure Assessment

This project develops novel analytical chemistry techniques for measuring low levels of toxic chemicals derived from SHS exposure, and biomarkers of SHS-induced cardiovascular injury. Co-Investigator: Peyton Jacob III, PhD
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Faculty Member:  Suzaynn F. Schick
Effects of aged sidestream cigarette smoke exposure on nasal congestion and inflammation

The aim of this study is to see if a 4 hour exposure to realistic levels of aged sidestream cigarette smoke can cause nasal congestion, the secretion of inflammatory compounds, or activation of genes involved in inflammatory responses in the noses of healthy nonsmokers.
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Faculty Member:  Suzaynn F. Schick
Effects of aged sidestream cigarette smoke exposure on lung inflammation

The aim of this study is to see if a 4 hour exposure to realistic levels of aged sidestream cigarette smoke can cause the recruitment of inflammatory cells, secretion of inflammatory compounds, or activation of genes involved in inflammatory responses in the lungs of healthy nonsmokers.
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Faculty Member:  Suzaynn F. Schick
Formation of the nitrosamine NNK in aging sidestream cigarette smoke

We will collect equal quantities of fresh and aged sidestream cigarette smoke particulates and quantify the carcinogenic tobacco specific N-nitrosamine NNK.
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FAMRI Clinic
The investigators are conducting a study to test whether exposure to second hand smoke causes negative effects on your health. In particular, the investigators wish to find out whether second-hand smoke exposure causes hidden heart or lung problems that are unmasked by exercise.
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