Tobacco Effects

The short and long term effects of cigarette smoking and other forms of tobacco use on health.
  • We are studying the effects of both active smoking and secondhand smoke exposure on susceptibility to acute lung injury, a major cause of respiratory failure among critically ill patients.

    Assistant Professor of Medicine
  •  Lung cancer is the leading cause of cancer death in both men and women. Lung cancer is unique because of racial disparity, persistent mortality rate, and social stigma. African- Americans are more likely than whites to avoid an evaluation for lung cancer, be diagnosed later with more advanced lung cancer, wait longer after diagnosis to receive treatment, refuse treatment, and more likely to die in the hospital after surgery.

    Associate Professor, Department of Physiological Nursing - Gerontology/Oncology
  • This work takes a transdisciplinary approach to develop a model for breast cancer causation and etiology that takes into account multiple disciplinary perspectives from the biologic to the sociologic in order to provide common ground for understanding and to point up gaps in knowledge about breast cancer etiology that require further investigation. Dr.

  • We are assessing the dose- and time-response of vascular functional impairment caused by exposure to second hand smoke at very low levels and short exposure times in rats.  

    Associate Professor of Medicine
  • AA and EA smokers undergo detailed monitoring of smoking behavior, receive known doses of nicotine to establish nicotine metabolic rate, undergo DNA testing, and have their responses to not smoking for several hours studied. Exposure to carcinogens and other tobacco smoke toxins is also measured.  It is hypothesized that there are racial differences in metabolism that may explain different patterns of smoking, and that this in turn influences the reasons why smokers continue to self-administer nicotine (i.e., continue to smoke).

    Professor of Medicine, Bioengineering and Therapeutic Sciences
  • The goal of this study was to examine the associations between the rate of nicotine metabolism and cigarette consumption, addiction and withdrawal symptoms.

    Assistant Adjunct Professor
  • These studies are funded by: 1) An R01 grant  from the National Heart, Lung and Blood Institute at the National Institutes of Health.

    Assistant Professor of Medicine in Residence
  • Cigarette smoking continues to be a major cause of cardiovascular disease (CVD). In contrast, the cardiovascular risks of other tobacco products in common use (smokeless tobacco) and new tobacco products (e-cigarettes) are not adequately understood. The FDA will need information about the cardiovascular safety of these products to inform their regulatory decisions.

    Professor in Residence, Cardiology, San Francisco General Hospital