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Comment: 

I believe the choice of biomarkers presented in your comment is biased and not representative of the results of the clinical studies. You have opted to not include markers which are by far more relevant to known disease risks caused by conventional smoking.

I would suggest that if anyone wants a balanced view of the results, that they read the full clinical study reports (CSRs) from FDA website to form their own unbiased views

Regards Thorsten

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