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I wasn't referring to MIs that happened before the advent of e-cigarettes (which I agree have little effect on the results), but more the smokers who had an MI (or other cardiac event) and then switched to e-cigarettes. Since we know there are a large number of smokers who are still unable to quit smoking after such events it is not only plausible, but probable that they would try e-cigarettes after having an MI. I fear that we won't be able to say definitively if e-cigarettes increase risk of heart disease until there are some long term longitudinal studies.

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