John Balmes, MD

Prrofessor in Residence
Medicine
+1 415 206-8314

Dr. Balmes received his MD degree from Mount Sinai School of Medicine in 1976. After internal medicine training at Mount Sinai and pulmonary subspecialty, occupational medicine, and research training at Yale, he joined the faculty of USC in 1982. He joined the faculty at UCSF in 1986 and is currently Professor and Division Chief of Occupational and Environmental Medicine at San Francisco General Hospital (SFGH). His major academic activities include his research laboratory, several collaborative epidemiological research projects, various advisory and editorial committees, and direction of the clinical occupational/environmental medicine division at SFGH.

Dr. Balmes' laboratory, the Human Exposure Laboratory (HEL), has been studying the respiratory health effects of various air pollutants for the past 27 years. Recently, the HEL has been focusing on the airway inflammatory effects of ozone, secondhand tobacco smoke, and wood smoke. The HEL was the first group to demonstrate a) histological evidence of ozone-induced airway injury and inflammation in human subjects, b) that asthmatic subjects have greater inflammatory responses to ozone than normal subjects, c) that ozone-induced inflammatory responses in normal subjects attenuate with short-term exposures on consecutive days in the lung, and d) that asthmatic subjects recruit macrophages to the airways with consecutive day exposures. The lab is currently studying the impact of a genetic polymorphism of the antioxidant enzyme, Glutathione-S-transferase M1, on the susceptibility of asthmatic subjects to ozone. We are also studying the relationship of acute airway inflammatory responses to acute cardiovascular responses after both ozone and secondhand tobacco smoke.

Dr. Balmes is also collaborating on several epidemiological projects that are run out of the UC Berkeley School of Public Health where he is a Professor of Environmental Health Sciences. One such project is called the Children’s Health and Air Pollution Study (CHAPS). The overall specific goal of CHAPS is to assess the impact of air pollution on the health of children living in the San Joaquin Valley, including adverse effects on immune function that may increase the risk of asthma onset and exacerbation. A second project involves study of the effects of biomass smoke exposure on chronic respiratory health of children and adult women in rural Guatemala. A third line of research involves the effects of arsenic in drinking water on lung health in both Bangladesh and Chile. Yet another project involves the effect of chronic exposure to hydrogen sulfide on lung function in Rotorua, NZ.

Publications: 

The Cooking and Pneumonia Study (CAPS) in Malawi: A Cross-Sectional Assessment of Carbon Monoxide Exposure and Carboxyhemoglobin Levels in Children under 5 Years Old.

International journal of environmental research and public health

Havens D, Wang D, Grigg J, Gordon SB, Balmes J, Mortimer K

Non-Communicable Respiratory Disease and Air Pollution Exposure in Malawi (CAPS): A Cross-Sectional Study.

American journal of respiratory and critical care medicine

Nightingale R, Lesosky M, Flitz G, Rylance SJ, Meghji J, Burney P, Balmes J, Mortimer K

Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma.

American journal of respiratory and critical care medicine

Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB

Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES).

Environment international

Rich DQ, Balmes JR, Frampton MW, Zareba W, Stark P, Arjomandi M, Hazucha MJ, Costantini MG, Ganz P, Hollenbeck-Pringle D, Dagincourt N, Bromberg PA

Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma.

Thorax

Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG

Influence of school environments on childhood obesity in California.

Environmental research

Ortega Hinojosa AM, MacLeod KE, Balmes J, Jerrett M

Lung cancer mortality and exposure to synthetic metalworking fluid and biocides: controlling for the healthy worker survivor effect.

Occupational and environmental medicine

Garcia E, Picciotto S, Neophytou AM, Bradshaw PT, Balmes JR, Eisen EA

Use of cleaner-burning biomass stoves and airway macrophage black carbon in Malawian women.

The Science of the total environment

Whitehouse AL, Miyashita L, Liu NM, Lesosky M, Flitz G, Ndamala C, Balmes JR, Gordon SB, Mortimer K, Grigg J

Household Air Pollution and Chronic Obstructive Pulmonary Disease. "A Riddle, Wrapped in a Mystery, Inside an Enigma".

American journal of respiratory and critical care medicine

Balmes JR, Eisen EA

Residential proximity to agricultural fumigant use and respiratory health in 7-year old children.

Environmental research

Gunier RB, Raanan R, Castorina R, Holland NT, Harley KG, Balmes JR, Fouquette L, Eskenazi B, Bradman A

Optimizing community-level surveillance data for pediatric asthma management.

Preventive medicine reports

Benka-Coker WO, Gale SL, Brandt SJ, Balmes JR, Magzamen S

Where There's Wildfire, There's Smoke.

The New England journal of medicine

Balmes JR

Exposure to NO2, CO, and PM2.5 is linked to regional DNA methylation differences in asthma.

Clinical epigenetics

Prunicki M, Stell L, Dinakarpandian D, de Planell-Saguer M, Lucas RW, Hammond SK, Balmes JR, Zhou X, Paglino T, Sabatti C, Miller RL, Nadeau KC

ERS/ATS workshop report on respiratory health effects of household air pollution.

The European respiratory journal

Sood A, Assad NA, Barnes PJ, Churg A, Gordon SB, Harrod KS, Irshad H, Kurmi OP, Martin WJ, Meek P, Mortimer K, Noonan CW, Perez-Padilla R, Smith KR, Tesfaigzi Y, Ward T, Balmes J

Respiratory Responses to Ozone Exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES).

American journal of respiratory and critical care medicine

Arjomandi M, Balmes JR, Frampton MW, Bromberg P, Rich DQ, Stark P, Alexis NE, Costantini M, Hollenbeck-Pringle D, Dagincourt N, Hazucha MJ

EPA's New Ozone Air Quality Standard: Why Should We Care?

Annals of the American Thoracic Society

Balmes JR

Environmental Effects of Intensive Livestock Farming.

American journal of respiratory and critical care medicine

Sigsgaard T, Balmes J

In control of ambient and household air pollution - how low should we go?

The Lancet. Respiratory medicine

Gordon S, Mortimer K, Grigg J, Balmes J

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California.

Environmental health perspectives

Blount RJ, Pascopella L, Catanzaro DG, Barry PM, English PB, Segal MR, Flood J, Meltzer D, Jones B, Balmes J, Nahid P

Elemental Sulfur Use and Associations with Pediatric Lung Function and Respiratory Symptoms in an Agricultural Community (California, USA).

Environmental health perspectives

Raanan R, Gunier RB, Balmes JR, Beltran AJ, Harley KG, Bradman A, Eskenazi B

The impact of BMI on non-malignant respiratory symptoms and lung function in arsenic exposed adults of Northern Chile.

Environmental research

Nardone A, Ferreccio C, Acevedo J, Enanoria W, Blair A, Smith AH, Balmes J, Steinmaus C

Effects of clinical and environmental factors on bronchoalveolar antibody responses to Pneumocystis jirovecii: A prospective cohort study of HIV+ patients.

PloS one

Blount RJ, Daly KR, Fong S, Chang E, Grieco K, Greene M, Stone S, Balmes J, Miller RF, Walzer PD, Huang L

Home monitoring improves endpoint efficiency in idiopathic pulmonary fibrosis.

The European respiratory journal

Johannson KA, Vittinghoff E, Morisset J, Lee JS, Balmes JR, Collard HR

The Effects of Bit Wear on Respirable Silica Dust, Noise and Productivity: A Hammer Drill Bench Study.

Annals of work exposures and health

Carty P, Cooper MR, Barr A, Neitzel RL, Balmes J, Rempel D

We Need to "Think Different" about Particulate Matter.

American journal of respiratory and critical care medicine

Thurston G, Balmes J

Occupational Exposure to Polycyclic Aromatic Hydrocarbon of Wildland Firefighters at Prescribed and Wildland Fires.

Environmental science & technology

Navarro KM, Cisneros R, Noth EM, Balmes JR, Hammond SK

AJRCCM: 100-Year Anniversary. Clearing the Air: Indoors, Outdoors, and At Work.

American journal of respiratory and critical care medicine

Balmes JR

An American Thoracic Society/National Heart, Lung, and Blood Institute Workshop Report: Addressing Respiratory Health Equality in the United States.

Annals of the American Thoracic Society

Celedón JC, Burchard EG, Schraufnagel D, Castillo-Salgado C, Schenker M, Balmes J, Neptune E, Cummings KJ, Holguin F, Riekert KA, Wisnivesky JP, Garcia JGN, Roman J, Kittles R, Ortega VE, Redline S, Mathias R, Thomas A, Samet J, Ford JG

Traffic-Related Air Pollution and Telomere Length in Children and Adolescents Living in Fresno, CA: A Pilot Study.

Journal of occupational and environmental medicine

Lee EY, Lin J, Noth EM, Hammond SK, Nadeau KC, Eisen EA, Balmes JR

Exhaled carbon monoxide: a non-invasive biomarker of short-term exposure to outdoor air pollution.

BMC public health

Lawin H, Ayi Fanou L, Hinson V, Wanjiku J, Ukwaja NK, Gordon SB, Fayomi B, Balmes JR, Houngbegnon P, Avokpaho E, Sanni A

Environment, Global Climate Change, and Cardiopulmonary Health.

American journal of respiratory and critical care medicine

Bayram H, Bauer AK, Abdalati W, Carlsten C, Pinkerton KE, Thurston GD, Balmes JR, Takaro TK

Air pollution, neighborhood acculturation factors, and neural tube defects among Hispanic women in California.

Birth defects research

Padula AM, Yang W, Carmichael SL, Lurmann F, Balmes J, Hammond SK, Shaw GM

A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework.

The European respiratory journal

Thurston GD, Kipen H, Annesi-Maesano I, Balmes J, Brook RD, Cromar K, De Matteis S, Forastiere F, Forsberg B, Frampton MW, Grigg J, Heederik D, Kelly FJ, Kuenzli N, Laumbach R, Peters A, Rajagopalan ST, Rich D, Ritz B, Samet JM, Sandstrom T, Sigsgaard T, Sunyer J, Brunekreef B

A cleaner burning biomass-fuelled cookstove intervention to prevent pneumonia in children under 5 years old in rural Malawi (the Cooking and Pneumonia Study): a cluster randomised controlled trial.

Lancet (London, England)

Mortimer K, Ndamala CB, Naunje AW, Malava J, Katundu C, Weston W, Havens D, Pope D, Bruce NG, Nyirenda M, Wang D, Crampin A, Grigg J, Balmes J, Gordon SB

National Institute of Environmental Health Sciences: 50 Years of Advancing Science and Improving Lung Health.

American journal of respiratory and critical care medicine

Antony VB, Redlich CA, Pinkerton KE, Balmes J, Harkema JR

Outdoor Air Pollution and Your Health.

American journal of respiratory and critical care medicine

Rice M, Balmes J, Malhotra A

Air-Quality Impacts and Intake Fraction of PM2.5 during the 2013 Rim Megafire.

Environmental science & technology

Navarro KM, Cisneros R, O'Neill SM, Schweizer D, Larkin NK, Balmes JR

High risks of lung disease associated with early-life and moderate lifetime arsenic exposure in northern Chile.

Toxicology and applied pharmacology

Steinmaus C, Ferreccio C, Acevedo J, Balmes JR, Liaw J, Troncoso P, Dauphiné DC, Nardone A, Smith AH

Survey of International Members of the American Thoracic Society on Climate Change and Health.

Annals of the American Thoracic Society

Sarfaty M, Kreslake J, Ewart G, Guidotti TL, Thurston GD, Balmes JR, Maibach EW

The last Summer Olympics? Climate change, health, and work outdoors.

Lancet (London, England)

Smith KR, Woodward A, Lemke B, Otto M, Chang CJ, Mance AA, Balmes J, Kjellstrom T

Differential respiratory health effects from the 2008 northern California wildfires: A spatiotemporal approach.

Environmental research

Reid CE, Jerrett M, Tager IB, Petersen ML, Mann JK, Balmes JR

Early-life ozone exposure associated with asthma without sensitization in Latino children.

The Journal of allergy and clinical immunology

Nishimura KK, Iwanaga K, Oh SS, Pino-Yanes M, Eng C, Keswani A, Roth LA, Nguyen EA, Thyne SM, Farber HJ, Serebrisky D, Meade K, LeNoir MA, Rodriguez-Cintron W, Borrell LN, Bibbins-Domingo K, Lurmann F, Sen S, Rodriguez-Santana JR, Brigino-Buenaventura E, Avila PC, Balmes JR, Kumar R, Burchard EG

Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies.

American journal of respiratory and critical care medicine

Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, Serebrisky D, Lenoir MA, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-Domingo K, Thyne SM, Williams LK, Sen S, Gilliland FD, Gauderman WJ, Rodriguez-Santana JR, Lurmann F, Balmes JR, Eisen EA, Burchard EG

Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome.

American journal of respiratory and critical care medicine

Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS

Critical Review of Health Impacts of Wildfire Smoke Exposure.

Environmental health perspectives

Reid CE, Brauer M, Johnston FH, Jerrett M, Balmes JR, Elliott CT

Lung function in woodsmoke-exposed Guatemalan children following a chimney stove intervention.

Thorax

Heinzerling AP, Guarnieri MJ, Mann JK, Diaz JV, Thompson LM, Diaz A, Bruce NG, Smith KR, Balmes JR

Decreased lung function in 7-year-old children with early-life organophosphate exposure.

Thorax

Raanan R, Balmes JR, Harley KG, Gunier RB, Magzamen S, Bradman A, Eskenazi B

Exposure to Endotoxin in Household Dust. To Wheeze or Not to Wheeze.

American journal of respiratory and critical care medicine

Balmes JR

Inflammatory and repair pathways induced in human bronchoalveolar lavage cells with ozone inhalation.

PloS one

Leroy P, Tham A, Wong H, Tenney R, Chen C, Stiner R, Balmes JR, Paquet AC, Arjomandi M

Chronic obstructive pulmonary disease secondary to household air pollution.

Seminars in respiratory and critical care medicine

Assad NA, Balmes J, Mehta S, Cheema U, Sood A

Exposure to medium and high ambient levels of ozone causes adverse systemic inflammatory and cardiac autonomic effects.

American journal of physiology. Heart and circulatory physiology

Arjomandi M, Wong H, Donde A, Frelinger J, Dalton S, Ching W, Power K, Balmes JR

Spatiotemporal prediction of fine particulate matter during the 2008 northern California wildfires using machine learning.

Environmental science & technology

Reid CE, Jerrett M, Petersen ML, Pfister GG, Morefield PE, Tager IB, Raffuse SM, Balmes JR

American Thoracic Society member survey on climate change and health.

Annals of the American Thoracic Society

Sarfaty M, Bloodhart B, Ewart G, Thurston GD, Balmes JR, Guidotti TL, Maibach EW

Cardiovascular risk and events and country income stratum.

The New England journal of medicine

Smith KR, Balmes JR, Guarnieri MJ

Ozone inhalation leads to a dose-dependent increase of cytogenetic damage in human lymphocytes.

Environmental and molecular mutagenesis

Holland N, Davé V, Venkat S, Wong H, Donde A, Balmes JR, Arjomandi M

An official American Thoracic Society statement: diagnosis and management of beryllium sensitivity and chronic beryllium disease.

American journal of respiratory and critical care medicine

Balmes JR, Abraham JL, Dweik RA, Fireman E, Fontenot AP, Maier LA, Muller-Quernheim J, Ostiguy G, Pepper LD, Saltini C, Schuler CR, Takaro TK, Wambach PF

Early-life exposure to organophosphate pesticides and pediatric respiratory symptoms in the CHAMACOS cohort.

Environmental health perspectives

Raanan R, Harley KG, Balmes JR, Bradman A, Lipsett M, Eskenazi B

Elevated lung cancer in younger adults and low concentrations of arsenic in water.

American journal of epidemiology

Steinmaus C, Ferreccio C, Yuan Y, Acevedo J, González F, Perez L, Cortés S, Balmes JR, Liaw J, Smith AH

Genetic modification of the effect of maternal household air pollution exposure on birth weight in Guatemalan newborns.

Reproductive toxicology (Elmsford, N.Y.)

Thompson LM, Yousefi P, Peñaloza R, Balmes J, Holland N

Developing small-area predictions for smoking and obesity prevalence in the United States for use in Environmental Public Health Tracking.

Environmental research

Ortega Hinojosa AM, Davies MM, Jarjour S, Burnett RT, Mann JK, Hughes E, Balmes JR, Turner MC, Jerrett M

Respiratory risks from household air pollution in low and middle income countries.

The Lancet. Respiratory medicine

Gordon SB, Bruce NG, Grigg J, Hibberd PL, Kurmi OP, Lam KB, Mortimer K, Asante KP, Balakrishnan K, Balmes J, Bar-Zeev N, Bates MN, Breysse PN, Buist S, Chen Z, Havens D, Jack D, Jindal S, Kan H, Mehta S, Moschovis P, Naeher L, Patel A, Perez-Padilla R, Pope D, Rylance J, Semple S, Martin WJ

Reply: the largest problem with climate change policy is not a future event.

American journal of respiratory and critical care medicine

Rice MB, Thurston GD, Balmes JR, Pinkerton KE

Ambient polycyclic aromatic hydrocarbons and pulmonary function in children.

Journal of exposure science & environmental epidemiology

Padula AM, Balmes JR, Eisen EA, Mann J, Noth EM, Lurmann FW, Pratt B, Tager IB, Nadeau K, Hammond SK

Perfluoroalkyl chemicals and asthma among children 12-19 years of age: NHANES (1999-2008).

Environmental health perspectives

Humblet O, Diaz-Ramirez LG, Balmes JR, Pinney SM, Hiatt RA

Outdoor air pollution and asthma.

Lancet (London, England)

Guarnieri M, Balmes JR

Effects of woodsmoke exposure on airway inflammation in rural Guatemalan women.

PloS one

Guarnieri MJ, Diaz JV, Basu C, Diaz A, Pope D, Smith KR, Smith-Sivertsen T, Bruce N, Solomon C, McCracken J, Balmes JR

Climate change. A global threat to cardiopulmonary health.

American journal of respiratory and critical care medicine

Rice MB, Thurston GD, Balmes JR, Pinkerton KE

An integrated risk function for estimating the global burden of disease attributable to ambient fine particulate matter exposure.

Environmental health perspectives

Burnett RT, Pope CA, Ezzati M, Olives C, Lim SS, Mehta S, Shin HH, Singh G, Hubbell B, Brauer M, Anderson HR, Smith KR, Balmes JR, Bruce NG, Kan H, Laden F, Prüss-Ustün A, Turner MC, Gapstur SM, Diver WR, Cohen A

Millions dead: how do we know and what does it mean? Methods used in the comparative risk assessment of household air pollution.

Annual review of public health

Smith KR, Bruce N, Balakrishnan K, Adair-Rohani H, Balmes J, Chafe Z, Dherani M, Hosgood HD, Mehta S, Pope D, Rehfuess E

Acute exacerbation of idiopathic pulmonary fibrosis associated with air pollution exposure.

The European respiratory journal

Johannson KA, Vittinghoff E, Lee K, Balmes JR, Ji W, Kaplan GG, Kim DS, Collard HR

Social isolation: a predictor of mortality comparable to traditional clinical risk factors.

American journal of public health

Pantell M, Rehkopf D, Jutte D, Syme SL, Balmes J, Adler N

Case-control study of arsenic in drinking water and lung cancer in California and Nevada.

International journal of environmental research and public health

Dauphiné DC, Smith AH, Yuan Y, Balmes JR, Bates MN, Steinmaus C

Chronic respiratory symptoms in children following in utero and early life exposure to arsenic in drinking water in Bangladesh.

International journal of epidemiology

Smith AH, Yunus M, Khan AF, Ercumen A, Yuan Y, Smith MH, Liaw J, Balmes J, von Ehrenstein O, Raqib R, Kalman D, Alam DS, Streatfield PK, Steinmaus C

Climate change and respiratory health: current evidence and knowledge gaps.

Expert review of respiratory medicine

Takaro TK, Knowlton K, Balmes JR

Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies.

American journal of respiratory and critical care medicine

Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell LN, Bibbins-Domingo K, Rodriguez-Santana JR, Sen S, Lurmann F, Balmes JR, Burchard EG

Asbestos and lung cancer: what we know.

American journal of respiratory and critical care medicine

Balmes JR

Thirdhand cigarette smoke in an experimental chamber: evidence of surface deposition of nicotine, nitrosamines and polycyclic aromatic hydrocarbons and de novo formation of NNK.

Tobacco control

Schick SF, Farraro KF, Perrino C, Sleiman M, van de Vossenberg G, Trinh MP, Hammond SK, Jenkins BM, Balmes J

Associations of ambient hydrogen sulfide exposure with self-reported asthma and asthma symptoms.

Environmental research

Bates MN, Garrett N, Crane J, Balmes JR

Household air pollution: a call for studies into biomarkers of exposure and predictors of respiratory disease.

American journal of physiology. Lung cellular and molecular physiology

Rylance J, Gordon SB, Naeher LP, Patel A, Balmes JR, Adetona O, Rogalsky DK, Martin WJ

Higher environmental relative moldiness index values measured in homes of adults with asthma, rhinitis, or both conditions.

Environmental research

Blanc PD, Quinlan PJ, Katz PP, Balmes JR, Trupin L, Cisternas MG, Wymer L, Vesper SJ

Cyclist route choice, traffic-related air pollution, and lung function: a scripted exposure study.

Environmental health : a global access science source

Jarjour S, Jerrett M, Westerdahl D, de Nazelle A, Hanning C, Daly L, Lipsitt J, Balmes J

Drinking water arsenic in northern chile: high cancer risks 40 years after exposure cessation.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Steinmaus CM, Ferreccio C, Romo JA, Yuan Y, Cortes S, Marshall G, Moore LE, Balmes JR, Liaw J, Golden T, Smith AH

Thirty minute-exposure to aged cigarette smoke increases nasal congestion in nonsmokers.

Journal of toxicology and environmental health. Part A

Schick SF, van den Vossenberg G, Luo A, Whitlatch A, Jacob P, Balmes J, Shusterman D

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

Lancet (London, England)

Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, Amann M, Anderson HR, Andrews KG, Aryee M, Atkinson C, Bacchus LJ, Bahalim AN, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell ML, Blore JD, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce NG, Brunekreef B, Bryan-Hancock C, Bucello C, Buchbinder R, Bull F, Burnett RT, Byers TE, Calabria B, Carapetis J, Carnahan E, Chafe Z, Charlson F, Chen H, Chen JS, Cheng AT, Child JC, Cohen A, Colson KE, Cowie BC, Darby S, Darling S, Davis A, Degenhardt L, Dentener F, Des Jarlais DC, Devries K, Dherani M, Ding EL, Dorsey ER, Driscoll T, Edmond K, Ali SE, Engell RE, Erwin PJ, Fahimi S, Falder G, Farzadfar F, Ferrari A, Finucane MM, Flaxman S, Fowkes FG, Freedman G, Freeman MK, Gakidou E, Ghosh S, Giovannucci E, Gmel G, Graham K, Grainger R, Grant B, Gunnell D, Gutierrez HR, Hall W, Hoek HW, Hogan A, Hosgood HD, Hoy D, Hu H, Hubbell BJ, Hutchings SJ, Ibeanusi SE, Jacklyn GL, Jasrasaria R, Jonas JB, Kan H, Kanis JA, Kassebaum N, Kawakami N, Khang YH, Khatibzadeh S, Khoo JP, Kok C, Laden F, Lalloo R, Lan Q, Lathlean T, Leasher JL, Leigh J, Li Y, Lin JK, Lipshultz SE, London S, Lozano R, Lu Y, Mak J, Malekzadeh R, Mallinger L, Marcenes W, March L, Marks R, Martin R, McGale P, McGrath J, Mehta S, Mensah GA, Merriman TR, Micha R, Michaud C, Mishra V, Mohd Hanafiah K, Mokdad AA, Morawska L, Mozaffarian D, Murphy T, Naghavi M, Neal B, Nelson PK, Nolla JM, Norman R, Olives C, Omer SB, Orchard J, Osborne R, Ostro B, Page A, Pandey KD, Parry CD, Passmore E, Patra J, Pearce N, Pelizzari PM, Petzold M, Phillips MR, Pope D, Pope CA, Powles J, Rao M, Razavi H, Rehfuess EA, Rehm JT, Ritz B, Rivara FP, Roberts T, Robinson C, Rodriguez-Portales JA, Romieu I, Room R, Rosenfeld LC, Roy A, Rushton L, Salomon JA, Sampson U, Sanchez-Riera L, Sanman E, Sapkota A, Seedat S, Shi P, Shield K, Shivakoti R, Singh GM, Sleet DA, Smith E, Smith KR, Stapelberg NJ, Steenland K, Stöckl H, Stovner LJ, Straif K, Straney L, Thurston GD, Tran JH, Van Dingenen R, van Donkelaar A, Veerman JL, Vijayakumar L, Weintraub R, Weissman MM, White RA, Whiteford H, Wiersma ST, Wilkinson JD, Williams HC, Williams W, Wilson N, Woolf AD, Yip P, Zielinski JM, Lopez AD, Murray CJ, Ezzati M, AlMazroa MA, Memish ZA

Mediators of the socioeconomic gradient in outcomes of adult asthma and rhinitis.

American journal of public health

Trupin L, Katz PP, Balmes JR, Chen H, Yelin EH, Omachi T, Blanc PD

Particulate matter and the environmental protection agency: setting the right standard.

American journal of respiratory cell and molecular biology

Thurston GD, Balmes JR

Household air pollution is a major avoidable risk factor for cardiorespiratory disease.

Chest

Mortimer K, Gordon SB, Jindal SK, Accinelli RA, Balmes J, Martin WJ

OBSTRUCTIVE LUNG DISEASE AND EXPOSURE TO BURNING BIOMASS FUEL IN THE INDOOR ENVIRONMENT.

Global heart

Diette GB, Accinelli RA, Balmes JR, Buist AS, Checkley W, Garbe P, Hansel NN, Kapil V, Gordon S, Lagat DK, Yip F, Mortimer K, Perez-Padilla R, Roth C, Schwaninger JM, Punturieri A, Kiley J

Utility of urinary Clara cell protein (CC16) to demonstrate increased lung epithelial permeability in non-smokers exposed to outdoor secondhand smoke.

Journal of exposure science & environmental epidemiology

St Helen G, Holland NT, Balmes JR, Hall DB, Bernert JT, Vena JE, Wang JS, Naeher LP

The exposure-dependent effects of aged secondhand smoke on endothelial function.

Journal of the American College of Cardiology

Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF

Polycyclic aromatic hydrocarbon exposure and wheeze in a cohort of children with asthma in Fresno, CA.

Journal of exposure science & environmental epidemiology

Gale SL, Noth EM, Mann J, Balmes J, Hammond SK, Tager IB

Exposure to secondhand smoke outside of a bar and a restaurant and tobacco exposure biomarkers in nonsmokers.

Environmental health perspectives

St Helen G, Bernert JT, Hall DB, Sosnoff CS, Xia Y, Balmes JR, Vena JE, Wang JS, Holland NT, Naeher LP

Effects of exercise on systemic inflammatory, coagulatory, and cardiac autonomic parameters in an inhalational exposure study.

Journal of occupational and environmental medicine

Donde A, Wong H, Frelinger J, Power K, Balmes JR, Arjomandi M

An official American Thoracic Society workshop report: Climate change and human health.

Proceedings of the American Thoracic Society

Pinkerton KE, Rom WN, Akpinar-Elci M, Balmes JR, Bayram H, Brandli O, Hollingsworth JW, Kinney PL, Margolis HG, Martin WJ, Sasser EN, Smith KR, Takaro TK

Pilot evaluation of the nasal nitric oxide response to humming as an index of osteomeatal patency.

American journal of rhinology & allergy

Shusterman DJ, Weaver EM, Goldberg AN, Schick SF, Wong HH, Balmes JR

Evaluation of a heat vulnerability index on abnormally hot days: an environmental public health tracking study.

Environmental health perspectives

Reid CE, Mann JK, Alfasso R, English PB, King GC, Lincoln RA, Margolis HG, Rubado DJ, Sabato JE, West NL, Woods B, Navarro KM, Balmes JR

Clearing the air.

American journal of respiratory and critical care medicine

Balmes J, Pinkerton K

The association between chronic exposure to traffic-related air pollution and ischemic heart disease.

Journal of toxicology and environmental health. Part A

Beckerman BS, Jerrett M, Finkelstein M, Kanaroglou P, Brook JR, Arain MA, Sears MR, Stieb D, Balmes J, Chapman K

Effect of reduction in household air pollution on childhood pneumonia in Guatemala (RESPIRE): a randomised controlled trial.

Lancet (London, England)

Smith KR, McCracken JP, Weber MW, Hubbard A, Jenny A, Thompson LM, Balmes J, Diaz A, Arana B, Bruce N

The role of physical inactivity in increasing disability among older adults with obstructive airway disease.

Journal of cardiopulmonary rehabilitation and prevention

Katz P, Chen H, Omachi TA, Gregorich SE, Julian L, Cisternas M, Balmes J, Blanc PD

Evaluating quality of life in patients with asthma and rhinitis: English adaptation of the rhinasthma questionnaire.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

Chen H, Cisternas MG, Katz PP, Omachi TA, Trupin L, Yelin EH, Balmes JR, Blanc PD

Lung function in adults following in utero and childhood exposure to arsenic in drinking water: preliminary findings.

International archives of occupational and environmental health

Dauphiné DC, Ferreccio C, Guntur S, Yuan Y, Hammond SK, Balmes J, Smith AH, Steinmaus C

Ambient air pollution impairs regulatory T-cell function in asthma.

The Journal of allergy and clinical immunology

Nadeau K, McDonald-Hyman C, Noth EM, Pratt B, Hammond SK, Balmes J, Tager I

An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease.

American journal of respiratory and critical care medicine

Eisner MD, Anthonisen N, Coultas D, Kuenzli N, Perez-Padilla R, Postma D, Romieu I, Silverman EK, Balmes JR

Short-term effects of air pollution on wheeze in asthmatic children in Fresno, California.

Environmental health perspectives

Mann JK, Balmes JR, Bruckner TA, Mortimer KM, Margolis HG, Pratt B, Hammond SK, Lurmann FW, Tager IB

Low prevalence of chronic beryllium disease among workers at a nuclear weapons research and development facility.

Journal of occupational and environmental medicine

Arjomandi M, Seward J, Gotway MB, Nishimura S, Fulton GP, Thundiyil J, King TE, Harber P, Balmes JR

An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study.

Environmental health : a global access science source

Trupin L, Balmes JR, Chen H, Eisner MD, Hammond SK, Katz PP, Lurmann F, Quinlan PJ, Thorne PS, Yelin EH, Blanc PD

When smoke gets in your lungs.

Proceedings of the American Thoracic Society

Balmes JR

A second chance. Setting a protective ozone standard.

American journal of respiratory and critical care medicine

Dey R, Van Winkle L, Ewart G, Balmes J, Pinkerton K

Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, California.

Journal of epidemiology and community health

Meng YY, Rull RP, Wilhelm M, Lombardi C, Balmes J, Ritz B

An official American thoracic society statement: position statement on ATS activities for the promotion of respiratory and sleep/wake health and the care of the critically ill in the United States.

American journal of respiratory and critical care medicine

Brown LK, Angus DC, Marin MG, Balmes JR, Barker AF, Ewart G, Halbower AC, Lutz PO, Mularski RA, Nathanson IT, Sanders MH, Stewart GL, Upson DJ

Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Eisner MD, Jacob P, Benowitz NL, Balmes J, Blanc PD

Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease.

Journal of occupational and environmental medicine

Blanc PD, Eisner MD, Earnest G, Trupin L, Balmes JR, Yelin EH, Gregorich SE, Katz PP

American College of Chest Physicians consensus statement on the respiratory health effects of asbestos. Results of a Delphi study.

Chest

Banks DE, Shi R, McLarty J, Cowl CT, Smith D, Tarlo SM, Daroowalla F, Balmes J, Baumann M

Altered pulmonary function in children with asthma associated with highway traffic near residence.

International journal of environmental health research

Margolis HG, Mann JK, Lurmann FW, Mortimer KM, Balmes JR, Hammond SK, Tager IB

Progression from beryllium exposure to chronic beryllium disease: an analytic model.

Environmental health perspectives

Harber P, Bansal S, Balmes J

Exposure to traffic: lung function and health status in adults with asthma.

The Journal of allergy and clinical immunology

Balmes JR, Earnest G, Katz PP, Yelin EH, Eisner MD, Chen H, Trupin L, Lurmann F, Blanc PD

Early-lifetime exposure to air pollution and allergic sensitization in children with asthma.

The Journal of asthma : official journal of the Association for the Care of Asthma

Mortimer K, Neugebauer R, Lurmann F, Alcorn S, Balmes J, Tager I

Controlled exposure to combined particles and ozone decreases heart rate variability.

Journal of occupational and environmental medicine

Power KL, Balmes J, Solomon C

Diagnosis and management of work-related asthma: American College Of Chest Physicians Consensus Statement.

Chest

Tarlo SM, Balmes J, Balkissoon R, Beach J, Beckett W, Bernstein D, Blanc PD, Brooks SM, Cowl CT, Daroowalla F, Harber P, Lemiere C, Liss GM, Pacheco KA, Redlich CA, Rowe B, Heitzer J

Air pollution and pulmonary function in asthmatic children: effects of prenatal and lifetime exposures.

Epidemiology (Cambridge, Mass.)

Mortimer K, Neugebauer R, Lurmann F, Alcorn S, Balmes J, Tager I

Brief secondhand smoke exposure depresses endothelial progenitor cells activity and endothelial function: sustained vascular injury and blunted nitric oxide production.

Journal of the American College of Cardiology

Heiss C, Amabile N, Lee AC, Real WM, Schick SF, Lao D, Wong ML, Jahn S, Angeli FS, Minasi P, Springer ML, Hammond SK, Glantz SA, Grossman W, Balmes JR, Yeghiazarians Y

Is there an association between lifetime cumulative exposure and acute pulmonary responses to ozone?

Journal of occupational and environmental medicine

Arjomandi M, Tager IB, Bastaki M, Chen C, Holland N, Balmes JR

Socioeconomic gradients in tiotropium use among adults with COPD.

International journal of chronic obstructive pulmonary disease

Blanc PD, Eisner MD, Yelin EH, Earnest G, Balmes JR, Gregorich SE, Katz PP

Effects of chronic and acute ozone exposure on lipid peroxidation and antioxidant capacity in healthy young adults.

Environmental health perspectives

Chen C, Arjomandi M, Balmes J, Tager I, Holland N

Chronic obstructive pulmonary disease: does occupation matter?

American journal of respiratory and critical care medicine

Torén K, Balmes J

Ozone, a malady for all ages.

American journal of respiratory and critical care medicine

Pinkerton KE, Balmes JR, Fanucchi MV, Rom WN

Nxwisen, ntzarrin or ntzo'lin? Mapping children's respiratory symptoms among indigenous populations in Guatemala.

Social science & medicine (1982)

Thompson L, Diaz J, Jenny A, Diaz A, Bruce N, Balmes J

Secondhand smoke exposure, pulmonary function, and cardiovascular mortality.

Annals of epidemiology

Eisner MD, Wang Y, Haight TJ, Balmes J, Hammond SK, Tager IB

The World Trade Center collapse: a continuing tragedy for lung health?

American journal of respiratory and critical care medicine

Balmes JR

Integrating research, surveillance, and practice in environmental public health tracking.

Environmental health perspectives

Kyle AD, Balmes JR, Buffler PA, Lee PR

Directly measured secondhand smoke exposure and COPD health outcomes.

BMC pulmonary medicine

Eisner MD, Balmes J, Yelin EH, Katz PP, Hammond SK, Benowitz N, Blanc PD

Case report: a case of wood-smoke-related pulmonary disease.

Environmental health perspectives

Diaz JV, Koff J, Gotway MB, Nishimura S, Balmes JR

Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans.

Pharmacogenetics and genomics

Bastaki M, Huen K, Manzanillo P, Chande N, Chen C, Balmes JR, Tager IB, Holland N

Residential proximity to naturally occurring asbestos: health risk or ecologic fallacy?

American journal of respiratory and critical care medicine

Brodkin CA, Balmes JR, Redlich CA, Cullen MR

Work life of persons with asthma, rhinitis, and COPD: a study using a national, population-based sample.

Journal of occupational medicine and toxicology (London, England)

Yelin E, Katz P, Balmes J, Trupin L, Earnest G, Eisner M, Blanc P

Effects of multiday exposure to ozone on airway inflammation as determined using sputum induction.

Environmental health perspectives

Ratto J, Wong H, Liu J, Fahy J, Boushey H, Solomon C, Balmes J

Effects of nitrogen dioxide on allergic airway responses in subjects with asthma.

Journal of occupational and environmental medicine

Witten A, Solomon C, Abbritti E, Arjomandi M, Zhai W, Kleinman M, Balmes J

Bronchiectasis in persons with skin lesions resulting from arsenic in drinking water.

Epidemiology (Cambridge, Mass.)

Mazumder DN, Steinmaus C, Bhattacharya P, von Ehrenstein OS, Ghosh N, Gotway M, Sil A, Balmes JR, Haque R, Hira-Smith MM, Smith AH

Chronic exposure to ambient ozone and lung function in young adults.

Epidemiology (Cambridge, Mass.)

Tager IB, Balmes J, Lurmann F, Ngo L, Alcorn S, Künzli N

Functioning and psychological status among individuals with COPD.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Katz PP, Eisner MD, Yelin EH, Trupin L, Earnest G, Balmes J, Blanc PD

Evidence for excess colorectal cancer incidence among asbestos-exposed men in the Beta-Carotene and Retinol Efficacy Trial.

American journal of epidemiology

Aliyu OA, Cullen MR, Barnett MJ, Balmes JR, Cartmel B, Redlich CA, Brodkin CA, Barnhart S, Rosenstock L, Israel L, Goodman GE, Thornquist MD, Omenn GS

Decrements in lung function related to arsenic in drinking water in West Bengal, India.

American journal of epidemiology

von Ehrenstein OS, Mazumder DN, Yuan Y, Samanta S, Balmes J, Sil A, Ghosh N, Hira-Smith M, Haque R, Purushothamam R, Lahiri S, Das S, Smith AH

Exposure to vapors, gas, dust, or fumes: assessment by a single survey item compared to a detailed exposure battery and a job exposure matrix.

American journal of industrial medicine

Blanc PD, Eisner MD, Balmes JR, Trupin L, Yelin EH, Katz PP

Respiratory health effects related to occupational spray painting and welding.

Journal of occupational and environmental medicine

Hammond SK, Gold E, Baker R, Quinlan P, Smith W, Pandya R, Balmes J

Sputum induction and bronchoscopy for assessment of ozone-induced airway inflammation in asthma.

Chest

Arjomandi M, Schmidlin I, Girling P, Boylen K, Ferrando R, Balmes J

Repeated exposure to ozone increases alveolar macrophage recruitment into asthmatic airways.

American journal of respiratory and critical care medicine

Arjomandi M, Witten A, Abbritti E, Reintjes K, Schmidlin I, Zhai W, Solomon C, Balmes J

Development and validation of a survey-based COPD severity score.

Chest

Eisner MD, Trupin L, Katz PP, Yelin EH, Earnest G, Balmes J, Blanc PD

Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease.

Environmental health : a global access science source

Eisner MD, Balmes J, Katz PP, Trupin L, Yelin EH, Blanc PD

Impact of the home indoor environment on adult asthma and rhinitis.

Journal of occupational and environmental medicine

Blanc PD, Eisner MD, Katz PP, Yen IH, Archea C, Earnest G, Janson S, Masharani UB, Quinlan PJ, Hammond SK, Thorne PS, Balmes JR, Trupin L, Yelin EH

Occupational contribution to the burden of chronic obstructive pulmonary disease.

Journal of occupational and environmental medicine

Balmes JR

Predictors of lung cancer among asbestos-exposed men in the {beta}-carotene and retinol efficacy trial.

American journal of epidemiology

Cullen MR, Barnett MJ, Balmes JR, Cartmel B, Redlich CA, Brodkin CA, Barnhart S, Rosenstock L, Goodman GE, Hammar SP, Thornquist MD, Omenn GS

The Beta-Carotene and Retinol Efficacy Trial: incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping beta-carotene and retinol supplements.

Journal of the National Cancer Institute

Goodman GE, Thornquist MD, Balmes J, Cullen MR, Meyskens FL, Omenn GS, Valanis B, Williams JH

Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects.

Chest

Chen LL, Tager IB, Peden DB, Christian DL, Ferrando RE, Welch BS, Balmes JR

Influence of age, gender, and allergy status on nasal reactivity to inhaled chlorine.

Inhalation toxicology

Shusterman D, Murphy MA, Balmes J

Differences in nasal irritant sensitivity by age, gender, and allergic rhinitis status.

International archives of occupational and environmental health

Shusterman D, Murphy MA, Balmes J

Evaluating the use of a portable spirometer in a study of pediatric asthma.

Chest

Mortimer KM, Fallot A, Balmes JR, Tager IB

American Thoracic Society Statement: Occupational contribution to the burden of airway disease.

American journal of respiratory and critical care medicine

Balmes J, Becklake M, Blanc P, Henneberger P, Kreiss K, Mapp C, Milton D, Schwartz D, Toren K, Viegi G

Hard metal interstitial lung disease: high-resolution computed tomography appearance.

Journal of thoracic imaging

Gotway MB, Golden JA, Warnock M, Koth LL, Webb R, Reddy GP, Balmes JR

Aircraft cabin air recirculation and symptoms of the common cold.

JAMA

Zitter JN, Mazonson PD, Miller DP, Hulley SB, Balmes JR

Diesel exhaust and asthma: hypotheses and molecular mechanisms of action.

Environmental health perspectives

Pandya RJ, Solomon G, Kinner A, Balmes JR