This randomized trial examined the efficacy of bupropion when begun in the hospital setting.

We are investigating the determinants of nicotine/tobacco dependence among African American smokers and the relationship between dependence and smoke intake to understand tobacco-related disease risks within that population. Current studies include assessment of gender differences in nicotine intake and carcinogen exposure among African American light smokers (those who smoke ten or fewer cigarettes per day) and studies on racial and gender differences in smoke intake among African American and Caucasian smokers. 

Eastern Europe Center of Excellence for Nurses in Tobacco Control (EE-COE), is a collaboration between the International Society of Nurses in Cancer Care, UCSF & UCLA Schools of Nursing, and partners from the Czech Republic, Hungary, Slovenia, Slovakia, and Romania. The EE-COE partners have developed, and are currently implementing educational activities in each of the five countries. The goal of this collaboration was to build capacity among nurses in general practice and in oncology to implement evidence-based interventions with all patients who smoke.

Individuals with mental illness or addictive disorders account for a staggering 44% to 46% of the US tobacco market. The overall goal of this research is to identify efficacious strategies for treating tobacco dependence among adult smokers hospitalized with severe mental illness.

The study addresses the underlying roles that a wide spectrum of health and human services play in the long-term course of alcohol problems in a representative sample of dependent and problem drinkers drawn from a single county’s household population. Fundamental to health services research in the alcohol field is an understanding of the long-term course of problem drinking and how health and human services, including alcohol treatment and self-help, impact that course.

The primary aim of this study is to determine the efficacy and cost-effectiveness of an intensive smoking cessation intervention that utilizes extended cognitive-behavioral therapy (ECBT) and combination nicotine replacement (CNRT), consisting of nicotine patches and adjuvant nicotine replacement (choice of lozenge, gum, nasal spray, or inhaler).    Effective smoking cessation interventions have yet to be identified for alcohol-dependent smokers in early recovery.  The primary aim of this study is to determine the efficacy and cost-effectiveness of an intensive smoking cessation interventio

At the same time that regulations on tobacco and on opioid prescriptions have become more stringent, regulations on cannabis have become less stringent: as of 2019, 11 states had legalized recreational cannabis and an additional 22 states had legalized medical cannabis use. The effects of these diverging trends are not clear, in part due to dramatic differences in local policies. Our work assesses whether localities make consistent choices with respect to substance use policies, and which policies are associated with reduced substance use at the population level.

A randomized controlled trial to study the efficacy of an extended treatment for cigarette smoking in a clinical setting.

AA and EA smokers undergo detailed monitoring of smoking behavior, receive known doses of nicotine to establish nicotine metabolic rate, undergo DNA testing, and have their responses to not smoking for several hours studied. Exposure to carcinogens and other tobacco smoke toxins is also measured.  It is hypothesized that there are racial differences in metabolism that may explain different patterns of smoking, and that this in turn influences the reasons why smokers continue to self-administer nicotine (i.e., continue to smoke).

In the U.S. there has been tremendous success in the reduction of smoking prevalence. However, for older adults who make up over a quarter of the US population and are expected to double by 2050, the decrease in smoking prevalence has stalled. While overall tobacco use in the US has declined the smallest reductions have been among 45-64yos and men older than 65 actually had a 10% increase. There has been rapid growth in electronic cigarette use among older smokers and the most common reported reason for use is to quit smoking cigarettes.

In this large cluster randomized trial, we are evaluating the effectiveness of multiple types of social and monetary incentives for smoking cessation among low-income factory workers in Thailand.

Unlike smoking,conventional smokeless tobacco (ST) (moist snuff, known as dip and chewing tobacco) among US high school students is much higher among males (13%) than females (2%) and is especially high in rural areas.  In 2005, ST manufacturers spent over $250 million on marketing, including “new” ST products such as dissolvable films, compressed tobacco (e.g.