Peter Ganz, MD

Professor in Residence
Medicine

Dr. Ganz is the Chief of Cardiology and the Director of the Center of Excellence in Vascular Research at the San Francisco General Hospital. He is the Maurice Eliaser Distinguished Professor of Medicine at the University of California, San Francisco. Dr. Ganz has been a pioneer and a leader in translational vascular research. He has focused on understanding key elements of human atherosclerosis including the pathobiology of the human endothelium, the biology of vascular nitric oxide, systemic and vascular inflammatory responses and atherosclerotic plaque instability. As a member of the Tobacco Center of Regulatory Science, he is currently conducting studies that will inform the cardiovascular effects and potential harms of conventional, new or emerging tobacco products. Dr. Ganz has authored over 200 peer reviewed articles, many published in the most prestigious journals. He has served on steering committees of numerous clinical trials. Many fellows who worked in Dr. Ganz’s laboratory have gone onto key leadership positions in academic medicine nationally and internationally. Dr. Ganz received his M.D. from Harvard Medical School, completed his residency at the Massachusetts General Hospital and cardiovascular fellowship at the Brigham and Women’s Hospital. He spent 25 years directing research in the Cardiac Catheterization Laboratories at the Brigham and Women’s Hospital and Harvard Medical School, prior to arriving to the University of California, San Francisco in 2008.

Publications: 

Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification.

European heart journal

Dubin RF, Deo R, Ren Y, Wang J, Pico AR, Mychaleckyj JC, Kozlitina J, Arthur V, Lee H, Shah A, Feldman H, Bansal N, Zelnick L, Rao P, Sukul N, Raj DS, Mehta R, Rosas SE, Bhat Z, Weir MR, He J, Chen J, Kansal M, Kimmel PL, Ramachandran VS, Waikar SS, Segal MR, Ganz P, CRIC Study Investigators

The Princeton IV Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease.

Mayo Clinic proceedings

Köhler TS, Kloner RA, Rosen RC, Burnett AL, Blaha MJ, Ganz P, Goldstein I, Kim NN, Lue T, McVary KT, Mulhall JP, Parish SJ, Sadeghi-Nejad H, Sadovsky R, Sharlip ID, Miner M

HOT FLASHES AND SLEEP DISRUPTION IN A RANDOMIZED TRIAL IN MENOPAUSAL WOMEN.

American journal of obstetrics and gynecology

Pei M, Gibson CJ, Schembri M, Raghunathan H, Grady D, Ganz P, Huang AJ

Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy.

JAMA cardiology

Greenland P, Segal MR, McNeil RB, Parker CB, Pemberton VL, Grobman WA, Silver RM, Simhan HN, Saade GR, Ganz P, Mehta P, Catov JM, Bairey Merz CN, Varagic J, Khan SS, Parry S, Reddy UM, Mercer BM, Wapner RJ, Haas DM

Proceedings of PRINCETON IV: PDE5 inhibitors and cardiac health symposium.

Sexual medicine reviews

Rosen RC, Miner M, Burnett AL, Blaha MJ, Ganz P, Goldstein I, Kim N, Kohler T, Lue T, McVary K, Mulhall J, Parish SJ, Sadeghi-Nejad H, Sadovsky R, Sharlip I, Kloner RA

Association of Integrated Proteomic and Metabolomic Modules with Risk of Kidney Disease Progression.

Journal of the American Society of Nephrology : JASN

Schlosser P, Surapaneni AL, Borisov O, Schmidt IM, Zhou L, Anderson A, Deo R, Dubin R, Ganz P, He J, Kimmel PL, Li H, Nelson RG, Porter AC, Rahman M, Rincon-Choles H, Shah V, Unruh ML, Vasan RS, Zheng Z, Feldman HI, Waikar SS, Köttgen A, Rhee EP, Coresh J, Grams ME, Chronic Renal Insufficiency Cohort (CRIC) Study Investigators and the CKD Biomarkers Consortium

Princeton IV consensus guidelines: PDE5 inhibitors and cardiac health.

The journal of sexual medicine

Kloner RA, Burnett AL, Miner M, Blaha MJ, Ganz P, Goldstein I, Kim NN, Kohler T, Lue T, McVary KT, Mulhall JP, Parish SJ, Sadeghi-Nejad H, Sadovsky R, Sharlip ID, Rosen RC

Proteomics for heart failure risk stratification: a systematic review.

BMC medicine

Kuku KO, Oyetoro R, Hashemian M, Livinski AA, Shearer JJ, Joo J, Psaty BM, Levy D, Ganz P, Roger VL

Development and Validation of a Protein Risk Score for Mortality in Heart Failure : A Community Cohort Study.

Annals of internal medicine

Kuku KO, Shearer JJ, Hashemian M, Oyetoro R, Park H, Dulek B, Bielinski SJ, Larson NB, Ganz P, Levy D, Psaty BM, Joo J, Roger VL

Circulating Growth Differentiation Factors 11 and 8, Their Antagonists Follistatin and Follistatin-like-3, and Risk of Heart Failure in Elders.

The journals of gerontology. Series A, Biological sciences and medical sciences

Kizer JR, Patel S, Ganz P, Newman AB, Bhasin S, Lee SJ, Cawthon PM, LeBrasseur N, Shah SJ, Psaty BM, Tracy RP, Cummings SR

Evaluation of a large-scale aptamer proteomics platform among patients with kidney failure on dialysis.

PloS one

Ren Y, Ruan P, Segal M, Dobre M, Schelling JR, Banerjee U, Shafi T, Ganz P, Dubin RF, CRIC Study Investigators

Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8 and their Binding Proteins Follistatin and Follistatin-like protein-3 with Dementia and Cognition.

The journals of gerontology. Series A, Biological sciences and medical sciences

Newman AB, Patel S, Kizer J, Lee SJ, Bhasin S, Cawthon P, LeBrasseur N, Tracy RP, Ganz P, Cummings S

Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8 and their Binding Proteins Follistatin and Follistatin-like protein-3 with Measures of Skeletal Muscle Mass, Muscle Strength and Physical Function in Older Adu

The journals of gerontology. Series A, Biological sciences and medical sciences

Cawthon PM, Patel S, Newman AB, Bhasin S, Peng L, Tracy R, Kizer JR, Lee SJ, Ferrucci L, Ganz P, LeBrasseur NK, Cummings S

Proteomics of CKD progression in the chronic renal insufficiency cohort.

Nature communications

Dubin RF, Deo R, Ren Y, Wang J, Zheng Z, Shou H, Go AS, Parsa A, Lash JP, Rahman M, Hsu CY, Weir MR, Chen J, Anderson A, Grams ME, Surapaneni A, Coresh J, Li H, Kimmel PL, Vasan RS, Feldman H, Segal MR, Ganz P, CRIC Study Investigators, CKD Biomarkers Consortium

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life.

Science translational medicine

Walker KA, Chen J, Shi L, Yang Y, Fornage M, Zhou L, Schlosser P, Surapaneni A, Grams ME, Duggan MR, Peng Z, Gomez GT, Tin A, Hoogeveen RC, Sullivan KJ, Ganz P, Lindbohm JV, Kivimaki M, Nevado-Holgado AJ, Buckley N, Gottesman RF, Mosley TH, Boerwinkle E, Ballantyne CM, Coresh J

Proteomic cardiovascular risk assessment in chronic kidney disease.

European heart journal

Deo R, Dubin RF, Ren Y, Murthy AC, Wang J, Zheng H, Zheng Z, Feldman H, Shou H, Coresh J, Grams M, Surapaneni AL, Bhat Z, Cohen JB, Rahman M, He J, Saraf SL, Go AS, Kimmel PL, Vasan RS, Segal MR, Li H, Ganz P

Analytical and Biological Variability of a Commercial Modified Aptamer Assay in Plasma Samples of Patients with Chronic Kidney Disease.

The journal of applied laboratory medicine

Dubin RF, Deo R, Ren Y, Lee H, Shou H, Feldman H, Kimmel P, Waikar SS, Rhee EP, Tin A, Chen J, Coresh J, Go AS, Kelly T, Rao PS, Chen TK, Segal MR, Ganz P

Identification of Protein Biomarkers of the Dietary Approaches to Stop Hypertension Diet in Randomized Feeding Studies and Validation in an Observational Study.

Journal of the American Heart Association

Kim H, Lichtenstein AH, Ganz P, Du S, Tang O, Yu B, Chatterjee N, Appel LJ, Coresh J, Rebholz CM

Alterations in the Circulating Proteome Associated with Albuminuria.

Journal of the American Society of Nephrology : JASN

Kiernan E, Surapaneni A, Zhou L, Schlosser P, Walker KA, Rhee EP, Ballantyne CM, Deo R, Dubin RF, Ganz P, Coresh J, Grams ME

Plasma Protein Biomarkers of Healthy Dietary Patterns: Results from the Atherosclerosis Risk in Communities Study and the Framingham Heart Study.

The Journal of nutrition

Du S, Chen J, Kim H, Walker ME, Lichtenstein AH, Chatterjee N, Ganz P, Yu B, Vasan RS, Coresh J, Rebholz CM

Chronic E-Cigarette Use Impairs Endothelial Function on the Physiological and Cellular Levels.

Arteriosclerosis, thrombosis, and vascular biology

Mohammadi L, Han DD, Xu F, Huang A, Derakhshandeh R, Rao P, Whitlatch A, Cheng J, Keith RJ, Hamburg NM, Ganz P, Hellman J, Schick SF, Springer ML

Testican-2 Is Associated with Reduced Risk of Incident ESKD.

Journal of the American Society of Nephrology : JASN

Wen D, Zhou L, Zheng Z, Surapaneni A, Ballantyne CM, Hoogeveen RC, Shlipak MG, Waikar SS, Vasan RS, Kimmel PL, Dubin RF, Deo R, Feldman HI, Ganz P, Coresh J, Grams ME, Rhee EP, CKD Biomarkers Consortium

Hospitalized Patients With COVID-19 Have Higher Plasma Aldosterone-Renin Ratio and Lower ACE Activity Than Controls.

Journal of the Endocrine Society

Parikh NI, Arowolo F, Durstenfeld MS, Nah G, Njoroge J, Vittinghoff E, Long CS, Ganz P, Pearce D, Hsue P, Wu AHS, Hajizadeh N, Liu KD, Lynch KL

A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk.

Science translational medicine

Williams SA, Ostroff R, Hinterberg MA, Coresh J, Ballantyne CM, Matsushita K, Mueller CE, Walter J, Jonasson C, Holman RR, Shah SH, Sattar N, Taylor R, Lean ME, Kato S, Shimokawa H, Sakata Y, Nochioka K, Parikh CR, Coca SG, Omland T, Chadwick J, Astling D, Hagar Y, Kureshi N, Loupy K, Paterson C, Primus J, Simpson M, Trujillo NP, Ganz P

Effect of HIV-1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction.

Journal of the American Heart Association

Thakkar AB, Ma Y, Dela Cruz M, Wu Y, Arechiga V, Swaminathan S, Ganz P, Wu AHB, Scherzer R, Deeks S, Hsue PY

Proteins Associated with Risk of Kidney Function Decline in the General Population.

Journal of the American Society of Nephrology : JASN

Grams ME, Surapaneni A, Chen J, Zhou L, Yu Z, Dutta D, Welling PA, Chatterjee N, Zhang J, Arking DE, Chen TK, Rebholz CM, Yu B, Schlosser P, Rhee EP, Ballantyne CM, Boerwinkle E, Lutsey PL, Mosley T, Feldman HI, Dubin RF, Ganz P, Lee H, Zheng Z, Coresh J

Comparison of proteomic methods in evaluating biomarker-AKI associations in cardiac surgery patients.

Translational research : the journal of laboratory and clinical medicine

Liu RX, Thiessen-Philbrook HR, Vasan RS, Coresh J, Ganz P, Bonventre JV, Kimmel PL, Parikh CR

Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk.

Nature aging

Walker KA, Chen J, Zhang J, Fornage M, Yang Y, Zhou L, Grams ME, Tin A, Daya N, Hoogeveen RC, Wu A, Sullivan KJ, Ganz P, Zeger SL, Gudmundsson EF, Emilsson V, Launer LJ, Jennings LL, Gudnason V, Chatterjee N, Gottesman RF, Mosley TH, Boerwinkle E, Ballantyne CM, Coresh J

Impact of Kidney Function on the Blood Proteome and on Protein Cardiovascular Risk Biomarkers in Patients With Stable Coronary Heart Disease.

Journal of the American Heart Association

Yang J, Brody EN, Murthy AC, Mehler RE, Weiss SJ, DeLisle RK, Ostroff R, Williams SA, Ganz P

Mechanisms of Sodium-Glucose Cotransporter 2 Inhibition: Insights From Large-Scale Proteomics.

Diabetes care

Ferrannini E, Murthy AC, Lee YH, Muscelli E, Weiss S, Ostroff RM, Sattar N, Williams SA, Ganz P

Does Ambient Ozone or Other Pollutants Modify Effects of Controlled Ozone Exposure on Pulmonary Function?

Annals of the American Thoracic Society

Rich DQ, Thurston SW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Alexis NE, Ganz P, Zareba W, Thevenet-Morrison K, Koutrakis P, Frampton MW

Nonsurgical Periodontal Therapy in CKD: Findings of the Kidney and Periodontal Disease (KAPD) Pilot Randomized Controlled Trial.

Kidney medicine

Grubbs V, Garcia F, Vittinghoff E, Jue BL, Ryder M, Lovett DH, Offenbacher S, Taylor G, Ganz P, Bibbins-Domingo K, Powe NR

Plasma protein patterns as comprehensive indicators of health.

Nature medicine

Williams SA, Kivimaki M, Langenberg C, Hingorani AD, Casas JP, Bouchard C, Jonasson C, Sarzynski MA, Shipley MJ, Alexander L, Ash J, Bauer T, Chadwick J, Datta G, DeLisle RK, Hagar Y, Hinterberg M, Ostroff R, Weiss S, Ganz P, Wareham NJ

William Ganz and His Legacy.

Annals of internal medicine

Ganz T, Ganz P

Echocardiographic determination of pulmonary arterial capacitance.

The international journal of cardiovascular imaging

Papolos A, Fan E, Wagle RR, Foster E, Boyle AJ, Yeghiazarians Y, MacGregor JS, Grossman W, Schiller NB, Ganz P, Tison GH

Vascular Aging is Accelerated in Flight Attendants with Occupational Secondhand Smoke Exposure.

Journal of occupational and environmental medicine

Wei J, Shufelt C, Oestreicher Stock E, Mills C, Dhawan S, Jacob R, Torbati T, Cook-Wiens G, Benowitz N, Jacob P, Ganz P, Bairey Merz CN, Redberg R

Associations of microvascular dysfunction with cardiovascular outcomes: The cardiac, endothelial function and arterial stiffness in ESRD (CERES) cohort.

Hemodialysis international. International Symposium on Home Hemodialysis

Ayer A, Mills C, Donovan C, Christenson RH, Ganz P, Dubin RF

Cardiovascular injury induced by tobacco products: Assessment of risk factors and biomarkers of harm A Tobacco Center of Regulatory Science (TCORS) Compilation.

American journal of physiology. Heart and circulatory physiology

Conklin DJ, Schick SF, Blaha MJ, Carll AP, DeFilippis A, Ganz P, Hall ME, Hamburg NM, O'Toole TE, Reynolds LM, Srivastava S, Bhatnagar A

Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay.

The journal of applied laboratory medicine

Tin A, Yu B, Ma J, Masushita K, Daya N, Hoogeveen RC, Ballantyne CM, Couper D, Rebholz CM, Grams ME, Alonso A, Mosley T, Heiss G, Ganz P, Selvin E, Boerwinkle E, Coresh J

Unique Circulating MicroRNA profiles in HIV Infection.

Journal of acquired immune deficiency syndromes (1999)

Narla V, Bhakta N, Freedman JE, Tanriverdi K, Maka K, Deeks SG, Ganz P, Hsue P

IL-1ß Inhibition Reduces Atherosclerotic Inflammation in HIV Infection.

Journal of the American College of Cardiology

Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A

Higher incidence of vasodilator-induced left ventricular cavity dilation by PET when compared to treadmill exercise-ECHO in hypertrophic cardiomyopathy.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Lu DY, Yalçin H, Sivalokanathan S, Greenland GV, Vasquez N, Yalçin F, Zhao M, Valenta I, Ganz P, Pampaloni MH, Zimmerman S, Schindler TH, Abraham TP, Abraham MR

Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES).

Environment international

Rich DQ, Balmes JR, Frampton MW, Zareba W, Stark P, Arjomandi M, Hazucha MJ, Costantini MG, Ganz P, Hollenbeck-Pringle D, Dagincourt N, Bromberg PA

Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.

Circulation

Williams SA, Murthy AC, DeLisle RK, Hyde C, Malarstig A, Ostroff R, Weiss SJ, Segal MR, Ganz P

Sex differences in vascular dysfunction and cardiovascular outcomes: The cardiac, endothelial function, and arterial stiffness in ESRD (CERES) study.

Hemodialysis international. International Symposium on Home Hemodialysis

Guajardo I, Ayer A, Johnson AD, Ganz P, Mills C, Donovan C, Scherzer R, Shah SJ, Peralta CA, Dubin RF

Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection.

JAMA cardiology

Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY

In Reply.

Menopause (New York, N.Y.)

Huang AJ, Ganz P, Grady D, Cummings SR

Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV.

Journal of the American Heart Association

Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY

The Kidney and Periodontal Disease (KAPD) study: A pilot randomized controlled trial testing the effect of non-surgical periodontal therapy on chronic kidney disease.

Contemporary clinical trials

Grubbs V, Garcia F, Jue BL, Vittinghoff E, Ryder M, Lovett D, Carrillo J, Offenbacher S, Ganz P, Bibbins-Domingo K, Powe NR

Associations of Macro- and Microvascular Endothelial Dysfunction With Subclinical Ventricular Dysfunction in End-Stage Renal Disease.

Hypertension (Dallas, Tex. : 1979)

Dubin RF, Guajardo I, Ayer A, Mills C, Donovan C, Beussink L, Scherzer R, Ganz P, Shah SJ

Development and Validation of a Protein-Based Risk Score for Cardiovascular Outcomes Among Patients With Stable Coronary Heart Disease.

JAMA

Ganz P, Heidecker B, Hveem K, Jonasson C, Kato S, Segal MR, Sterling DG, Williams SA

HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox".

Journal of the American Heart Association

Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY

Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.

Circulation research

Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ, Lee RT

Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial.

Menopause (New York, N.Y.)

Huang AJ, Cummings SR, Schembri M, Vittinghoff E, Ganz P, Grady D

Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection.

PloS one

Parikh RV, Ma Y, Scherzer R, Heringer AS, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY

Behavioral Cardiovascular Risk Factors - Effect of Physical Activity and Cardiorespiratory Fitness on Cardiovascular Outcomes.

Circulation journal : official journal of the Japanese Circulation Society

Spencer RM, Heidecker B, Ganz P

Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts.

European heart journal

Olson KA, Beatty AL, Heidecker B, Regan MC, Brody EN, Foreman T, Kato S, Mehler RE, Singer BS, Hveem K, Dalen H, Sterling DG, Lawn RM, Schiller NB, Williams SA, Whooley MA, Ganz P

Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals.

JACC. Heart failure

Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY

Traditional Risk Factors Versus Biomarkers for Prediction of Secondary Events in Patients With Stable Coronary Heart Disease: From the Heart and Soul Study.

Journal of the American Heart Association

Beatty AL, Ku IA, Bibbins-Domingo K, Christenson RH, DeFilippi CR, Ganz P, Ix JH, Lloyd-Jones D, Omland T, Sabatine MS, Schiller NB, Shlipak MG, Skali H, Takeuchi M, Vittinghoff E, Whooley MA

Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling.

PloS one

Waldo SW, Brenner DA, McCabe JM, De la Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY

Utility of both carotid intima-media thickness and endothelial function for cardiovascular risk stratification in patients with angina-like symptoms.

International journal of cardiology

Matsuzawa Y, Svedlund S, Aoki T, Guddeti RR, Kwon TG, Cilluffo R, Widmer RJ, Nelson RE, Lennon RJ, Lerman LO, Gao S, Ganz P, Gan LM, Lerman A

A novel minimally-invasive method to sample human endothelial cells for molecular profiling.

PloS one

Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis.

Journal of the American Heart Association

Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J

Association of peripheral microvascular dysfunction and erectile dysfunction.

The Journal of urology

Gerber RE, Vita JA, Ganz P, Wager CG, Araujo AB, Rosen RC, Kupelian V

Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection.

AIDS (London, England)

Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY

All men with vasculogenic erectile dysfunction require a cardiovascular workup.

The American journal of medicine

Miner M, Nehra A, Jackson G, Bhasin S, Billups K, Burnett AL, Buvat J, Carson C, Cunningham G, Ganz P, Goldstein I, Guay A, Hackett G, Kloner RA, Kostis JB, LaFlamme KE, Montorsi P, Ramsey M, Rosen R, Sadovsky R, Seftel A, Shabsigh R, Vlachopoulos C, Wu F

Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms.

Journal of the American Heart Association

McCabe JM, Armstrong EJ, Ku I, Kulkarni A, Hoffmayer KS, Bhave PD, Waldo SW, Hsue P, Stein JC, Marcus GM, Kinlay S, Ganz P

Long-term outcomes of patients sent emergently to the catheterization laboratory for possible primary percutaneous coronary intervention.

The American journal of cardiology

Turner TE, Waldo SW, Kulkarni A, Armstrong EJ, Hoffmayer KS, Kinlay S, Hsue P, Ganz P, McCabe JM

Clinical characteristics and reperfusion times among patients with an isolated posterior myocardial infarction.

The Journal of invasive cardiology

Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer KS, Hsue P, Ganz P, McCabe JM

Emergency medical service utilization and door-to-balloon time for HIV-infected individuals with ST-elevation myocardial infarction.

International journal of cardiology

Brenner DA, Dela Cruz M, Thomas K, McCabe JM, Ganz P, Hsue PY, Waldo SW

Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals.

Atherosclerosis

Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY

Glycemic associations with endothelial function and biomarkers among 5 ethnic groups: the Multi-Ethnic Study of Atherosclerosis and the Mediators of Atherosclerosis in South Asians Living in America studies.

Journal of the American Heart Association

Kanaya AM, Dobrosielski DA, Ganz P, Creasman J, Gupta R, Nelacanti V, Vogel-Claussen J, Herrington D

Comparison of clinical characteristics and outcomes of cardiac arrest survivors having versus not having coronary angiography.

The American journal of cardiology

Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer K, Kinlay S, Hsue P, Ganz P, McCabe JM

Inflammatory biomarkers, death, and recurrent nonfatal coronary events after an acute coronary syndrome in the MIRACL study.

Journal of the American Heart Association

Zamani P, Schwartz GG, Olsson AG, Rifai N, Bao W, Libby P, Ganz P, Kinlay S

Impact of door-to-activation time on door-to-balloon time in primary percutaneous coronary intervention for ST-segment elevation myocardial infarctions: a report from the Activate-SF registry.

Circulation. Cardiovascular quality and outcomes

McCabe JM, Armstrong EJ, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P

The assessment of endothelial function: from research into clinical practice.

Circulation

Flammer AJ, Anderson T, Celermajer DS, Creager MA, Deanfield J, Ganz P, Hamburg NM, Lüscher TF, Shechter M, Taddei S, Vita JA, Lerman A

The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease.

Mayo Clinic proceedings

Nehra A, Jackson G, Miner M, Billups KL, Burnett AL, Buvat J, Carson CC, Cunningham GR, Ganz P, Goldstein I, Guay AT, Hackett G, Kloner RA, Kostis J, Montorsi P, Ramsey M, Rosen R, Sadovsky R, Seftel AD, Shabsigh R, Vlachopoulos C, Wu FC

Electrocardiographic criteria for ST-elevation myocardial infarction in patients with left ventricular hypertrophy.

The American journal of cardiology

Armstrong EJ, Kulkarni AR, Bhave PD, Hoffmayer KS, Macgregor JS, Stein JC, Kinlay S, Ganz P, McCabe JM

Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry.

Archives of internal medicine

McCabe JM, Armstrong EJ, Kulkarni A, Hoffmayer KS, Bhave PD, Garg S, Patel A, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P

Prognostic utility of erectile dysfunction for cardiovascular disease in younger men and those with diabetes.

American heart journal

Miner M, Seftel AD, Nehra A, Ganz P, Kloner RA, Montorsi P, Vlachopoulos C, Ramsey M, Sigman M, Tilkemeier P, Jackson G

The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease.

AIDS (London, England)

Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY

The exposure-dependent effects of aged secondhand smoke on endothelial function.

Journal of the American College of Cardiology

Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF

Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation.

Journal of the American Heart Association

Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG

Delaying primary percutaneous coronary intervention for computed tomographic scans in the emergency department.

The American journal of cardiology

Armstrong EJ, Kulkarni AR, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P, McCabe JM

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy.

Heart rhythm

Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM

Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium.

The American journal of cardiology

Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD

Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital.

Archives of internal medicine

Secemsky EA, Lange D, Ho JE, Brayton K, Ganz PA, Farr G, Macgregor JS, Hsue PY

Predictors of depressed left ventricular function in patients presenting with ST-elevation myocardial infarction.

The American journal of cardiology

Bhave PD, Hoffmayer KS, Armstrong EJ, Garg S, Patel A, Macgregor JS, Stein JC, Kinlay S, Ganz P, McCabe JM

Coronary circulatory function in patients with the metabolic syndrome.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Di Carli MF, Charytan D, McMahon GT, Ganz P, Dorbala S, Schelbert HR

Associations of endothelial dysfunction and arterial stiffness with intradialytic hypotension and hypertension.

Hemodialysis international. International Symposium on Home Hemodialysis

Dubin R, Owens C, Gasper W, Ganz P, Johansen K

High-resolution magnetic resonance imaging enhanced with superparamagnetic nanoparticles measures macrophage burden in atherosclerosis.

Circulation

Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M

AJC editor's consensus: rheumatoid arthritis and atherosclerotic cardiovascular disease.

The American journal of cardiology

Friedewald VE, Ganz P, Kremer JM, Mease PJ, O'Dell JR, Pearson TA, Ram CV, Ridker PM, Salmon JE, Roberts WC

Effect of vascular endothelial growth factor and its receptor KDR on the transendothelial migration and local trafficking of human T cells in vitro and in vivo.

Blood

Edelbauer M, Datta D, Vos IH, Basu A, Stack MP, Reinders ME, Sho M, Calzadilla K, Ganz P, Briscoe DM

Does erectile dysfunction contribute to cardiovascular disease risk prediction beyond the Framingham risk score?

Journal of the American College of Cardiology

Araujo AB, Hall SA, Ganz P, Chiu GR, Rosen RC, Kupelian V, Travison TG, McKinlay JB

Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients.

AIDS (London, England)

Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG

Endothelin-1 is a key mediator of coronary vasoconstriction in patients with transplant coronary arteriosclerosis.

Circulation. Heart failure

Larose E, Behrendt D, Kinlay S, Selwyn AP, Ganz P, Fang JC

Erectile dysfunction and mortality.

The journal of sexual medicine

Araujo AB, Travison TG, Ganz P, Chiu GR, Kupelian V, Rosen RC, Hall SA, McKinlay JB

Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis.

AIDS (London, England)

Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG

Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis.

Circulation journal : official journal of the Japanese Circulation Society

Ku IA, Imboden JB, Hsue PY, Ganz P

Is hyperlipidemia or its treatment associated with erectile dysfunction?: Results from the Boston Area Community Health (BACH) Survey.

The journal of sexual medicine

Hall SA, Kupelian V, Rosen RC, Travison TG, Link CL, Miner MM, Ganz P, McKinlay JB

Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event.

The American journal of cardiology

Rawlings R, Nohria A, Liu PY, Donnelly J, Creager MA, Ganz P, Selwyn A, Liao JK

Statins inhibit Rho kinase activity in patients with atherosclerosis.

Atherosclerosis

Nohria A, Prsic A, Liu PY, Okamoto R, Creager MA, Selwyn A, Liao JK, Ganz P

Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque.

Circulation

Serruys PW, García-García HM, Buszman P, Erne P, Verheye S, Aschermann M, Duckers H, Bleie O, Dudek D, Bøtker HE, von Birgelen C, D'Amico D, Hutchinson T, Zambanini A, Mastik F, van Es GA, van der Steen AF, Vince DG, Ganz P, Hamm CW, Wijns W, Zalewski A

Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study.

Arteriosclerosis, thrombosis, and vascular biology

Kinlay S, Schwartz GG, Olsson AG, Rifai N, Szarek M, Waters DD, Libby P, Ganz P

Improved characterization of atherosclerotic plaques by gadolinium contrast during intravascular magnetic resonance imaging of human arteries.

Atherosclerosis

Larose E, Kinlay S, Selwyn AP, Yeghiazarians Y, Yucel EK, Kacher DF, Libby P, Ganz P

Right ventricular dysfunction assessed by cardiovascular magnetic resonance imaging predicts poor prognosis late after myocardial infarction.

Journal of the American College of Cardiology

Larose E, Ganz P, Reynolds HG, Dorbala S, Di Carli MF, Brown KA, Kwong RY

Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease.

Circulation research

Nohria A, Grunert ME, Rikitake Y, Noma K, Prsic A, Ganz P, Liao JK, Creager MA

Role of nitric oxide in the regulation of digital pulse volume amplitude in humans.

Journal of applied physiology (Bethesda, Md. : 1985)

Nohria A, Gerhard-Herman M, Creager MA, Hurley S, Mitra D, Ganz P

Impact of coronary endothelial function on the progression of cardiac transplant-associated arteriosclerosis: effect of anti-oxidant vitamins C and E.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Behrendt D, Beltrame J, Hikiti H, Wainstein M, Kinlay S, Selwyn AP, Ganz P, Fang JC

Effect of ACAT inhibition on the progression of coronary atherosclerosis.

The New England journal of medicine

Nissen SE, Tuzcu EM, Brewer HB, Sipahi I, Nicholls SJ, Ganz P, Schoenhagen P, Waters DD, Pepine CJ, Crowe TD, Davidson MH, Deanfield JE, Wisniewski LM, Hanyok JJ, Kassalow LM

Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference).

The American journal of cardiology

Kostis JB, Jackson G, Rosen R, Barrett-Connor E, Billups K, Burnett AL, Carson C, Cheitlin M, Debusk R, Fonseca V, Ganz P, Goldstein I, Guay A, Hatzichristou D, Hollander JE, Hutter A, Katz S, Kloner RA, Mittleman M, Montorsi F, Montorsi P, Nehra A, Sadovsky R, Shabsigh R

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging.

Circulation

Larose E, Yeghiazarians Y, Libby P, Yucel EK, Aikawa M, Kacher DF, Aikawa E, Kinlay S, Schoen FJ, Selwyn AP, Ganz P

Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference).

The American journal of cardiology

Kostis JB, Jackson G, Rosen R, Barrett-Connor E, Billups K, Burnett AL, Carson C, Cheitlin M, Debusk R, Fonseca V, Ganz P, Goldstein I, Guay A, Hatzichristou D, Hollander JE, Hutter A, Katz S, Kloner RA, Mittleman M, Montorsi F, Montorsi P, Nehra A, Sadovsky R, Shabsigh R

High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial.

European heart journal

Olsson AG, Schwartz GG, Szarek M, Sasiela WJ, Ezekowitz MD, Ganz P, Oliver MF, Waters D, Zeiher A

Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease.

The New England journal of medicine

Nissen SE, Tuzcu EM, Schoenhagen P, Crowe T, Sasiela WJ, Tsai J, Orazem J, Magorien RD, O'Shaughnessy C, Ganz P

Statins and endothelial dysfunction.

Seminars in vascular medicine

Larose E, Ganz P

Comparison of endothelial function in young men and women with a family history of premature coronary artery disease.

The American journal of cardiology

Hamburg NM, Charbonneau F, Gerhard-Herman M, Ganz P, Creager MA

Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial.

JAMA

Nissen SE, Tuzcu EM, Schoenhagen P, Brown BG, Ganz P, Vogel RA, Crowe T, Howard G, Cooper CJ, Brodie B, Grines CL, DeMaria AN

Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function.

Journal of the American College of Cardiology

Kinlay S, Behrendt D, Fang JC, Delagrange D, Morrow J, Witztum JL, Rifai N, Selwyn AP, Creager MA, Ganz P

Early statin therapy in acute coronary syndromes.

Seminars in vascular medicine

Kinlay S, Ganz P

High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study.

Circulation

Kinlay S, Schwartz GG, Olsson AG, Rifai N, Leslie SJ, Sasiela WJ, Szarek M, Libby P, Ganz P

Endothelin-1 and vascular tone in subjects with atherogenic risk factors.

Hypertension (Dallas, Tex. : 1979)

Nohria A, Garrett L, Johnson W, Kinlay S, Ganz P, Creager MA

Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells.

Circulation

Schönbeck U, Gerdes N, Varo N, Reynolds RS, Horton DB, Bavendiek U, Robbie L, Ganz P, Kinlay S, Libby P

Circulating autoantibodies to oxidized LDL correlate with impaired coronary endothelial function after cardiac transplantation.

Arteriosclerosis, thrombosis, and vascular biology

Fang JC, Kinlay S, Behrendt D, Hikita H, Witztum JL, Selwyn AP, Ganz P

Endothelial function. From vascular biology to clinical applications.

The American journal of cardiology

Behrendt D, Ganz P

Contribution of endothelin to pulmonary vascular tone under normoxic and hypoxic conditions.

American journal of physiology. Heart and circulatory physiology

Johnson W, Nohria A, Garrett L, Fang JC, Igo J, Katai M, Ganz P, Creager MA

Coronary flow velocity and disturbed flow predict adverse clinical outcome after coronary angioplasty.

Arteriosclerosis, thrombosis, and vascular biology

Kinlay S, Grewal J, Manuelin D, Fang JC, Selwyn AP, Bittl JA, Ganz P

Vasomotor and vascular effects of hormone replacement therapy.

The American journal of cardiology

Ganz P

Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial.

Lancet (London, England)

Fang JC, Kinlay S, Beltrame J, Hikiti H, Wainstein M, Behrendt D, Suh J, Frei B, Mudge GH, Selwyn AP, Ganz P