Immune Effects of Cannabinoids and the Endocannabinoid System


  1. Judith Hellman, MD
Research Fields: 

We are doing basic-translational research on the immune modulating effects of cannabis-derived and endogenous cannabinoids. We have found that phytocannabinoids, such as THC and several minor cannabinoids have anti-inflammatory effects in vitro on leukocytes and endothelial cells, and in vivo in models of acute systemic inflammation. We are currently studying the anti-inflammatory mechanisms of cannabis-derived cannabinoids and endocannabinoids, and their effects on inflammatory pain and on inflammatory critical illness.