Tobacco Center Faculty Blog

October 6, 2017

Stanton A. Glantz, PhD

Andreas Lappas and colleagues just published “Short-term respiratory effects of e-cigarettes in healthy individuals and smokers with asthma,”  which shows that when smokers use an e-cigarette, it worsens lung function, with bigger effects in smokers who already have asthma.
 
This is an important finding because it indicates that dual use of cigarettes and e-cigarettes, by far the most common use pattern, is worse than smoking alone.
 
Here is the abstract:
 
Background and objective:  This study investigated the duration of immediate respiratory effects of e-cigarette smoking (ECS) and tested the hypothesis that ECS has more prominent effects in asthmatics compared with healthy smokers (HS).
Methods; Fifty-four smokers, 27 healthy (HS group) and 27 with intermittent asthma (mild asthma (MA) group) underwent a control session (no liquid, no resistor coil inside e-cigarette cartridge) and an experimental session of ECS using standardized puffing settings. Impulse oscillometry impedance (Z), resistance (R), reactance (X) and fractional exhaled nitric oxide (FeNO) were measured before and 0, 15 and 30 min after control and experimental sessions.

October 2, 2017

Stanton A. Glantz, PhD

This comment was submitted to Regulations.gov on October 2, 2017; the tracking number is  1k1-8yzw-s3z7. A PDF version of the letter is available here.
 
I urge other organzations, whether they are planning comments or not, to submit similar letters.
 
October 2, 2017
 
Mr. Mitchell Zeller
Director, Center for Tobacco Products
Food and Drug Administration
10903 New Hampshire Avenue
Silver Spring, MD 20993 
 
Re: 82 FR 27487, Docket no. FDA-2017-D-3001 for Modified Risk Tobacco Product Applications: Applications for IQOS System With Marlboro Heatsticks, IQOS System With Marlboro Smooth Menthol Heatsticks, and IQOS System With Marlboro Fresh Menthol Heatsticks Submitted by Philip Morris Products S.A.; Availability
 
Dear Mr. Zeller:
 

September 29, 2017

Stanton A. Glantz, PhD

Rebecca J. Schweitzer and colleagues just published “E-cigarette use and asthma in a multiethnic sample of adolescents” in Preventive Medicine.  This paper adds to the growing case that e-cigarettes have adverse effects on lung health and health in general.  The odds of having asthma are increased by about 50% among adolescents who are using e-cigarettes, controlling for cigarette smoking and other risk factors.  The fact that there was an increased risk even among current smokers adds to the case that e-cigarettes have their own risk profile on top of cigarettes.
 
 The effects are larger among Blacks, Native Hawaiians, other Pacific Islanders, and Filipinos than Caucasians and Asians.
 
Here is the abstract:
 

September 15, 2017

Stanton A. Glantz, PhD

The UN Global Compact is an initiative to engage companies “to align strategies and operations with universal principles on human rights, labour, environment and anti-corruption, and take actions that advance societal goals.” 
 
Given the fact that the tobacco industry works consistently against human rights, the environment, and is a huge corrupting force in the word, it has always been irritating that the UNGC allowed them as members.  The industry, of course, then used their membership as part of the “corporate social responsibility” PR efforts.  In particular, the industry has worked to undermine implementation of the WHO Framework Convention on Tobacco Control, a UN treaty.
 
Thanks to the efforts of many people and countries for several years, the UNGC is throwing the tobacco companies out.  Here is their announcement, issued a few days ago:
 
UN Global Compact Integrity Policy Update
Updated 12 September 2017
 

September 14, 2017

Stanton A. Glantz, PhD

Hong-Jun Cho, Lauren Dutra, and I recently published “Differences in adolescent e-cigarette and cigarette prevalence in two policy environments: South Korea and the United States” in Nicotine and Tobacco Research.  This paper compares changes in e-cigarette and cigarette use in South Korea and the United States between 2011 and 2015.  Korea has maintained restrictive policies on e-cigarettes whereas the US has left them essentially unregulated (a situation that the FDA will continue until at least 2022). 
 
We found that In Korea adolescent e-cigarette use remained stable at a low level, whereas in the United States e-cigarette use increased.  Most important, combined e-cigarette plus cigarette use declined in Korea whereas it increased in the US. The restrictive policies in Korea likely contributed to lower overall tobacco product use.  These results are evidence against the claims that the availability of e-cigarettes is preventing youth from taking up cigarettes.  They also add to the case that a permissive e-cigarette policy environment is making the overall nicotine/tobacco epidemic worse.  It is also
 
Here is the abstract:
 

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