Addiction and Cessation

The nature and severity of nicotine addiction, treatement strategies, and the health benefits of quitting.
  • The primary aim of this study is to determine the efficacy and cost-effectiveness of an intensive smoking cessation intervention that utilizes extended cognitive-behavioral therapy (ECBT) and combination nicotine replacement (CNRT), consisting of nicotine patches and adjuvant nicotine replacement (choice of lozenge, gum, nasal spray, or inhaler).   

    Clinical Professor, Department of Psychiatry
  • This project aims to estimate the relative impact of two intervention approaches for generating community pharmacy-based referrals to tobacco cessation telephone quitlines. This study will apply a randomized design, using the community pharmacy as the unit of randomization, to estimate the impact of two approaches for engaging community pharmacy personnel in providing patient referrals to tobacco quitlines: (1) Minimal intervention: Pharmacies are provided, by mail, with printed quitline materials to be distributed by pharmacy personnel to patients who smoke. (2) Academic detailing: Pharmacy personnel receive, via brief on-site training, print materials that parallel the minimal intervention group, fax referral forms, and DVD demonstrations that model the referral procedures.

    Professor of Clinical Pharmacy
  • The study addresses the underlying roles that a wide spectrum of health and human services play in the long-term course of alcohol problems in a representative sample of dependent and problem drinkers drawn from a single county’s household population. Fundamental to health services research in the alcohol field is an understanding of the long-term course of problem drinking and how health and human services, including alcohol treatment and self-help, impact that course.

    Professor of Biostatistics in Psychiatry
  • Tobacco dependence continues to be the single most preventable cause of morbidity and mortality in the United States. Persons entering drug abuse treatment smoke at 3-4 times the rate, and staff in publicly funded programs smoke at twice the rate, of the general population. Although the burden of illness and associated economic costs of nicotine addiction are elevated in the drug treatment population, treatment programs rarely address comorbid nicotine addiction.

    Professor in Residence
  • A randomized controlled trial to study the efficacy of an extended treatment for cigarette smoking in a clinical setting.

    Professor in Residence, Psychiatry
  • Individuals with mental illness or addictive disorders account for a staggering 44% to 46% of the US tobacco market. The overall goal of this research is to identify efficacious strategies for treating tobacco dependence among adult smokers hospitalized with severe mental illness.

    Associate Professor of Medicine, Stanford Prevention Research Center, Stanford Univ
  • This randomized trial examined the efficacy of bupropion when begun in the hospital setting.

    Professor of Clinical Medicine
  • The goal of this study was to examine the associations between the rate of nicotine metabolism and cigarette consumption, addiction and withdrawal symptoms.

  • This descriptive study consists of focus groups and survey development to explore among African American smokers perceived obstacles in the use of nicotine replacement therapy and to identify any uses of alternative medicines as aids to help them quit smoking.

    Associate Professor
  • Unlike smoking,conventional smokeless tobacco (ST) (moist snuff, known as dip and chewing tobacco) among US high school students is much higher among males (13%) than females (2%) and is especially high in rural areas.  In 2005, ST manufacturers spent over $250 million on marketing, including “new” ST products such as dissolvable films, compressed tobacco (e.g.

    Professor, School of Dentistry
  • Eastern Europe Center of Excellence for Nurses in Tobacco Control (EE-COE), is a collaboration between the International Society of Nurses in Cancer Care, UCSF & UCLA Schools of Nursing, and partners from the Czech Republic, Hungary, Slovenia, Slovakia, and Romania. The EE-COE partners have developed, and are currently implementing educational activities in each of the five countries. The goal of this collaboration was to build capacity among nurses in general practice and in oncology to implement evidence-based interventions with all patients who smoke.

    Associate Professor in Residence, Department of Social Behavioral Sciences
  • Although the 5A’s for smoking cessation is an accepted standard of care, national data show that most primary care providers fail to adhere to the full intervention guidelines.  This NIDA-funded implementation science R01 tests the use of a hybrid delivery model for the 5A’s in primary care that could improve intervention fidelity, save clinician time, and still utilize the social influence of the provider.  This model is being tested in a randomized-controlled trial at 3 UCSF primary care clinics.

    Professor of Clinical Medicine, UCSF
  • In this large cluster randomized trial, we are evaluating the effectiveness of multiple types of social and monetary incentives for smoking cessation among low-income factory workers in Thailand.

    Assistant Professor of Health Economics
  • Tobacco use remains the largest preventable cause of death in the United States[i]. Tobacco cessation involves multiple quit attempts over time—but with provider engagement, patients are more likely to remain smoke-free. A 2014 Cochrane review showed that documentation of tobacco use and referral to cessation counseling appeared to increase following implementation of EMR-based tools[ii].

    Assistant Clinical Professor of Medicine, Division of General Internal Medicine