Judith Hellman, MD
My research program is focused on basic and translational research on sepsis and other forms of inflammation-driven acute organ failure ("Inflammatory Critical Illness"). Sepsis and multiple organ failure are leading causes of death in the Intensive Care Unit. These processes result from a complex inflammatory response that is initiated through the innate immune system by interactions between host cells and microbes or endogenous host factors that are released during injury or cell death. The family of Toll-like receptors (TLRs) recognize different microbial components and endogenous host factors, and are critical in initiating inflammatory responses to infection. The Hellman Group studies TLR-dependent pathways expressed by macrophages as well as non-conventional inflammatory cells, including endothelial cells, in Inflammatory Critical Illness, focusing on their roles in coagulopathy, vascular permeability, neutrophil trafficking to organs, and organ injury and failure.
Carolyn Hendrickson, MD, MPH
Effect of smoke on Acute Respiratory Distress Syndrome
Robert Hiatt, MD
Cancer epidemiology and studies of cancer etiology, early development, the environment and social determinants.
Cristin Kearns, DDS, MBA
Establishing food industry documents research as a new area of investigation that transforms the way people think about sugar and the sugar industry’s role in promoting health inequities related to dental caries, obesity, heart disease, and diabetes.
Lisa Kroon, PharmD
Tobacco cessation education and training of health professionals.
Susan Lee, MD
Feasibility and acceptability of e-cigarettes versus nicotine replacement therapy for smoking cessation in the perioperative period.
Heather Leutwyler, RN, PhD, NP
Dr. Leutwyler has extensive research and clinical experiences working with adults with serious mental illness, and her research focuses on identifying factors associated with poor physical health among adults with schizophrenia and conducting interventions to promote physical health among adults with serious mental illness. Currently, Dr. Leutwyler is the PI of a TRDRP-funded pilot 2-arm RCT to examine the feasibility and potential efficacy of a game-based group physical activity intervention, along with cessation counseling and pharmacotherapy, to increase successful smoking cessation in smokers with serious mental illness.
James Lightwood, PhD
Estimating the changes in direct healthcare costs due to changes in smoking behavior in large populations, and changes in exposure to passive smoking and health care cost and utilization attributable to adoption of smoke-free laws.